These are all facts we need to become comfortable with to live the best way. My take on the 17th submission is that while we should hold the mindset that we are responsible for how our life goes, if we try everything to make something work and it doesn't, we should not beat ourselves up, because while we assume that we have 100% responsibility over everything happening in our lives, there are still factors beyond our control. Sometimes in life, our best efforts may not be enough. But it's better to fail after trying than to fail because you didn't try at all or enough.